Large melanocytic nevi in generalized atrophic benign epidermolysis bullosa (epidermolysis bullosa nevi)

被引：12

作者：

Bichel, J ^{[1
]}

Metze, D ^{[1
]}

Bruckner-Tuderman, L ^{[1
]}

Ständer, S ^{[1
]}

机构：

[1] Univ Munster, Hautklin, D-48149 Munster, Germany

来源：

HAUTARZT | 2001年 / 52卷 / 09期

关键词：

melanocytic nevi; generalized atrophic benign epidermolysis bullosa; GABEB; epidermolysis-bullosa-nevi;

D O I：

10.1007/s001050170072

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Generalized atrophic benign epidermolysis bullosa (GABEB) is a nonlethal form of junctional epidermolysis bullosa. The expression of type XVII collagen (180 kDa bullous pemphigoid antigen) or of laminin 5 is markedly reduced in the skin. A 13-year-old patient with GABEB, developed several large, asymmetric, irregularly pigmented melanocytic nevi with poorly defined borders. They had appeared following blister formation since 8 years of age. Histological examination revealed an irregular proliferation of monomorphous melanocytes at the dermoepidermal junction. Small nests of melanocytes were focally present. This case further emphasizes the difficulty in differentiating nevi appearing in GABEB from malignant melanoma.

引用

页码：812 / 816

页数：5

共 22 条

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[2]

BAUER JW, IN PRESS J AM ACAD D

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