What is antibiotic resistance and how can we measure it?

被引：60

作者：

Davison, HC ^{[1
]}

Low, JC

Woolhouse, MEJ

机构：

[1] Univ Edinburgh, Ctr Trop Vet Med, Roslin EH25 9RG, Midlothian, Scotland

[2] Scottish Agr Coll, Vet Sci Div, Edinburgh EH26 0QE, Midlothian, Scotland

来源：

TRENDS IN MICROBIOLOGY | 2000年 / 8卷 / 12期

关键词：

D O I：

10.1016/S0966-842X(00)01873-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Antibiotic resistance is being found with increasing frequency in both pathogenic and commensal bacteria of humans and animals. Quantifying resistance within and between bacterial and host populations presents scientists with complex challenges in terms of laboratory methodologies and sampling design. Here, we discuss, from an epidemiological perspective, how antibiotic resistance can be defined and measured and the limitations of current approaches.

引用

页码：554 / 559

页数：6

共 48 条

[1] PREVALENCE OF ANTIBIOTIC-RESISTANT ESCHERICHIA-COLI IN DANISH PIGS AND CATTLE [J].

AALBAEK, B ;

RASMUSSEN, J ;

NIELSEN, B ;

OLSEN, JE .

APMIS, 1991, 99 (12) :1103-1110

[2]

[Anonymous], 1991, J Antimicrob Chemother, V27 Suppl D, P1

[3]

BAGER F, 1999, DANMAP 98 CONSUMPTIO

[4] Preventing antibiotic resistance through rapid genotypic identification of bacteria and of their antibiotic resistance genes in the clinical microbiology laboratory [J].

Bergeron, MG ;

Ouellette, M .

JOURNAL OF CLINICAL MICROBIOLOGY, 1998, 36 (08) :2169-2172

[5] Monitoring of antibiotic resistance in bacteria of animal origin: epidemiological and microbiological methodologies [J].

Caprioli, A ;

Busani, L ;

Martel, JL ;

Helmuth, R .

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2000, 14 (04) :295-301

[6] AN EVALUATION OF METHODS TO ASSESS THE EFFECT OF ANTIMICROBIAL RESIDUES ON THE HUMAN GUT FLORA [J].

CORPET, DE .

VETERINARY MICROBIOLOGY, 1993, 35 (3-4) :199-212

[7] INACTIVATION OF ANTIBIOTICS AND THE DISSEMINATION OF RESISTANCE GENES [J].

DAVIES, J .

SCIENCE, 1994, 264 (5157) :375-382

[8]

Davis MW, 1998, KLUW S INF, V2, P11

[9] Antimicrobial susceptibility of Staphylococcus aureus isolated from bovine mastitis in Europe and the United States [J].

De Oliveira, AP ;

Watts, JL ;

Salmon, SA ;

Aerestrup, FM .

JOURNAL OF DAIRY SCIENCE, 2000, 83 (04) :855-862

[10] Sampling considerations for herd-level measurement of faecal Escherichia coli antimicrobial resistance in finisher pigs [J].

Dunlop, RH ;

McEwen, SA ;

Meek, AH ;

Friendship, RM ;

Black, WD ;

Clarke, RC .

EPIDEMIOLOGY AND INFECTION, 1999, 122 (03) :485-496

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