Magnetic nanoparticles: biomedical applications and challenges

被引：351

作者：

Tran, Nhiem ^{[2
]}

Webster, Thomas J. ^{[1
,3
]}

机构：

[1] Brown Univ, Sch Engn, Providence, RI 02912 USA

[2] Brown Univ, Dept Phys, Providence, RI 02912 USA

[3] Brown Univ, Dept Orthopaed, Providence, RI 02912 USA

来源：

JOURNAL OF MATERIALS CHEMISTRY | 2010年 / 20卷 / 40期

关键词：

IRON-OXIDE NANOPARTICLES; FLUID HYPERTHERMIA MFH; DRUG-DELIVERY; SUPERPARAMAGNETIC NANOPARTICLES; PROSTATE-CANCER; IN-VITRO; ANTIBACTERIAL PROPERTIES; TARGETED DELIVERY; CONTRAST AGENTS; PHASE-I;

D O I：

10.1039/c0jm00994f

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070305 [高分子化学与物理];

摘要：

The progress in the development of magnetic nanoparticle based therapies for various biomedical applications is reviewed here. Most significantly, magnetic nanoparticles have been widely used in drug delivery and hyperthermia treatment for cancer. However, recent applications of magnetic nanoparticles demonstrate their promise towards decreasing implant infection and increasing tissue growth. To build the most effective magnetic nanoparticle systems for various biomedical applications, particle characteristics including size, surface chemistry, magnetic properties and toxicity have to be fully investigated. In this review, several new applications of magnetic nanoparticles in the medical arena as well as remaining challenges for such clinical use are discussed.

引用

页码：8760 / 8767

页数：8

共 123 条

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