Lipases in Cachexia

被引：29

作者：

Arner, Peter ^{[1
]}

机构：

[1] Karolinska Univ Hosp, Dept Med, Karolinska Inst, S-14186 Stockholm, Sweden

来源：

SCIENCE | 2011年 / 333卷 / 6039期

关键词：

CANCER CACHEXIA; ADIPOSE-TISSUE; LIPOLYSIS; FAT;

D O I：

10.1126/science.1209418

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

070301 [无机化学]; 070403 [天体物理学]; 070507 [自然资源与国土空间规划学]; 090105 [作物生产系统与生态工程];

摘要：

引用

收藏

页码：163 / 164

页数：2

相关论文

共 11 条

[1]

Mechanism of increased lipolysis in cancer cachexia [J].

Agustsson, Thorhallur ;

Ryden, Mikael ;

Hoffstedt, Johan ;

van Harmelen, Vanessa ;

Dicker, Andrea ;

Laurencikiene, Jurga ;

Isaksson, Bengt ;

Permert, Johan ;

Arner, Peter .

CANCER RESEARCH, 2007, 67 (11) :5531-5537

[2]

Evidence for a Novel Serum Factor Distinct From Zinc Alpha-2 Glycoprotein That Promotes Body Fat Loss Early in the Development of Cachexia [J].

Byerley, Lauri O. ;

Lee, Sang Ho ;

Redmann, Steve ;

Culberson, Cathy ;

Clemens, Mark ;

Lively, Mark O. .

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 2010, 62 (04) :484-494

[3]

Specific inhibition of hormone-sensitive lipase improves lipid profile while reducing plasma glucose [J].

Claus, TH ;

Lowe, DB ;

Liang, Y ;

Salhanick, AI ;

Lubeski, CK ;

Yang, L ;

Lemoine, L ;

Zhu, J ;

Clairmont, KB .

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2005, 315 (03) :1396-1402

[4]

Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia [J].

Das, Suman K. ;

Eder, Sandra ;

Schauer, Silvia ;

Diwoky, Clemens ;

Temmel, Hannes ;

Guertl, Barbara ;

Gorkiewicz, Gregor ;

Tamilarasan, Kuppusamy P. ;

Kumari, Pooja ;

Trauner, Michael ;

Zimmermann, Robert ;

Vesely, Paul ;

Haemmerle, Guenter ;

Zechner, Rudolf ;

Hoefler, Gerald .

SCIENCE, 2011, 333 (6039) :233-238

[5]

Body composition and time course changes in regional distribution of fat and lean tissue in unselected cancer patients on palliative care -: Correlations with food intake, metabolism, exercise capacity, and hormones [J].

Fouladiun, M ;

Körner, U ;

Bosaeus, I ;

Daneryd, P ;

Hyltander, A ;

Lundholm, KG .

CANCER, 2005, 103 (10) :2189-2198

[6]

WHOLE-BODY LIPOLYSIS AND TRIGLYCERIDE-FATTY ACID CYCLING IN CACHECTIC PATIENTS WITH ESOPHAGEAL CANCER [J].

KLEIN, S ;

WOLFE, RR .

JOURNAL OF CLINICAL INVESTIGATION, 1990, 86 (05) :1403-1408

[7]

Natriuretic peptides and other biomarkers in chronic heart failure: From BNP, NT-proBNP, and MR-proANP to routine biochemical markers [J].

Lainscak, Mitja ;

von Haehling, Stephan ;

Anker, Stefan D. .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2009, 132 (03) :303-311

[8]

Lipolysis - A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores [J].

Lass, Achim ;

Zimmermann, Robert ;

Oberer, Monika ;

Zechner, Rudolf .

PROGRESS IN LIPID RESEARCH, 2011, 50 (01) :14-27

[9]

Enhanced ZAG production by subcutaneous adipose tissue is linked to weight loss in gastrointestinal cancer patients [J].

Mracek, T. ;

Stephens, N. A. ;

Gao, D. ;

Bao, Y. ;

Ross, J. A. ;

Ryden, M. ;

Arner, P. ;

Trayhurn, P. ;

Fearon, K. C. H. ;

Bing, C. .

BRITISH JOURNAL OF CANCER, 2011, 104 (03) :441-447

[10]

Lipolysis -: Not inflammation, cell death, or lipogenesis -: Is involved in adipose tissue loss in cancer cachexia [J].

Ryden, Mikael ;

Agustsson, Thorhallur ;

Laurencikiene, Jurga ;

Britton, Tom ;

Sjoelin, Eva ;

Isaksson, Bengt ;

Permert, Johan ;

Arner, Peter .

CANCER, 2008, 113 (07) :1695-1704