Gray matter decrease in patients with chronic tension type headache

被引：360

作者：

Schmidt-Wilcke, T

Leinisch, E

Straube, A

Kämpfe, N

Draganski, B

Diener, HC

Bogdahn, U

May, A

机构：

[1] Univ Hamburg, Krankenhaus Eppendorf, Dept Syst Neurosci, D-20246 Hamburg, Germany

[2] Univ Regensburg, Dept Neurol, D-8400 Regensburg, Germany

[3] Univ Munich, Dept Neurol, D-8000 Munich, Germany

[4] Univ Essen Gesamthsch, Dept Neurol, D-4300 Essen, Germany

来源：

NEUROLOGY | 2005年 / 65卷 / 09期

关键词：

D O I：

10.1212/01.wnl.0000183067.94400.80

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Using MRI and voxel-based morphometry, the authors investigated 20 patients with chronic tension type headache (CTTH) and 20 patients with medication-overuse headache and compared them to 40 controls with no headache history. Only patients with CTTH demonstrated a significant gray matter decrease in regions known to be involved in pain processing. The finding implies that the alterations are specific to CTTH rather than a response to chronic head pain or chronification per se.

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页码：1483 / 1486

页数：4

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