Significance of lymphocytic sister chromatid exchange frequencies in ovarian cancer patients

被引：15

作者：

Dhar, PK

Devi, S

Rao, TR

Kumari, U

Joseph, A

Kumar, MR

Nayak, S

Shreemati, Y

Bhat, SM

Bhat, KR

机构：

[1] KASTURBA MED COLL & HOSP,DEPT PHYSIOL,MANIPAL 576119,KARNATAKA,INDIA

[2] KASTURBA MED COLL & HOSP,DEPT MED EDUC,MANIPAL 576119,KARNATAKA,INDIA

来源：

CANCER GENETICS AND CYTOGENETICS | 1996年 / 89卷 / 02期

关键词：

D O I：

10.1016/0165-4608(95)00071-2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Very few studies report the analysis of sister chromatid exchanges in ovarian cancer patients. We tested the null hypothesis that SCE frequency increases with the advancing stages of ovarian cancer and follows a Poisson distribution. As controls we examined age- and sex-matched healthy volunteers who had no such past history. An increased overage SCE frequency was observed in ovarian cancer patients (6.34 +/- 0.09) vis-a-vis controls (4.47 +/- 0.12). Further, the data also suggested a stage-wise increase in the SCE frequency.

引用

页码：105 / 108

页数：4

共 13 条

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VARIATION IN SPONTANEOUS CHROMOSOMAL DAMAGE AS A FUNCTION OF BIOLOGIC RHYTHMS IN WOMEN [J].