Addition of Z-vinylic higher order cyanocuprates to enones followed by O-functionalization

被引：36

作者：

Moraes, DN ^{[1
]}

Barrientos-Astigarraga, RE ^{[1
]}

Castelani, P ^{[1
]}

Comasseto, JV ^{[1
]}

机构：

[1] Univ Sao Paulo, Inst Quim, BR-05599070 Sao Paulo, Brazil

来源：

TETRAHEDRON | 2000年 / 56卷 / 21期

基金：

巴西圣保罗研究基金会;

关键词：

Z-vinylic tellurides; higher order cyanocuprates; conjugated addition; vinyl triflates; vinyl phosphates; silyl enol ethers;

D O I：

10.1016/S0040-4020(00)00254-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Transmetalation reaction between Z-vinylic tellurides and higher order cyanocuprates generated the corresponding Z-vinylic cyanocuprates. Conjugate addition of these cuprates to enones followed by O-functionalization led to silyl enol ethers, vinyl phosphates and vinyl triflates. The vinyl triflates were transformed into highly unsaturated systems by coupling with alkynes or with Z-vinyl zinc chlorides under Pd (0) catalysis. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：3327 / 3337

页数：11

共 31 条

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