InSatDb: a microsatellite database of fully sequenced insect genomes

被引:35
作者
Archak, Sunil [1 ]
Meduri, Eshwar [1 ]
Kumar, P. Sravana [1 ]
Nagaraju, J. [1 ]
机构
[1] Ctr DNA Fingerprinting & Diagnost, Genet Mol Lab, Hyderabad 500076, Andhra Pradesh, India
关键词
D O I
10.1093/nar/gkl778
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
InSatDb presents an interactive interface to query information regarding microsatellite characteristics per se of five fully sequenced insect genomes (fruit-fly, honeybee, malarial mosquito, red-flour beetle and silkworm). InSatDb allows users to obtain microsatellites annotated with size (in base pairs and repeat units); genomic location (exon, intron, up-stream or transposon); nature (perfect or imperfect); and sequence composition (repeat motif and GC%). One can access microsatellite cluster (compound repeats) information and a list of microsatellites with conserved flanking sequences (microsatellite family or paralogs). InSatDb is complete with the insects information, web links to find details, methodology and a tutorial. A separate 'Analysis' section illustrates the comparative genomic analysis that can be carried out using the output. InSatDb is available at www.cdfd.org.in/insatdb.
引用
收藏
页码:D36 / D39
页数:4
相关论文
共 16 条
[1]   Tandem repeats finder: a program to analyze DNA sequences [J].
Benson, G .
NUCLEIC ACIDS RESEARCH, 1999, 27 (02) :573-580
[2]   Short fuzzy tandem repeats in genomic sequences, identification, and possible role in regulation of gene expression [J].
Boeva, V ;
Regnier, M ;
Papatsenko, D ;
Makeev, V .
BIOINFORMATICS, 2006, 22 (06) :676-684
[3]   Tandem repeats in protein coding regions of primate genes [J].
Borstnik, B ;
Pumpernik, D .
GENOME RESEARCH, 2002, 12 (06) :909-915
[4]   Prediction of complete gene structures in human genomic DNA [J].
Burge, C ;
Karlin, S .
JOURNAL OF MOLECULAR BIOLOGY, 1997, 268 (01) :78-94
[5]   Two distinct modes of microsatellite mutation processes:: Evidence from the complete genomic sequences of nine species [J].
Dieringer, D ;
Schlötterer, C .
GENOME RESEARCH, 2003, 13 (10) :2242-2251
[6]  
Karaoglu H, 2005, MOL BIOL EVOL, V22, P639, DOI [10.1093/molbev/msi057, 10.1093/molbev/mis057]
[7]   Simple sequence repeats as advantageous mutators in evolution [J].
Kashi, Yechezkel ;
King, David G. .
TRENDS IN GENETICS, 2006, 22 (05) :253-259
[8]   Differential distribution of simple sequence repeats in eukaryotic genome sequences [J].
Katti, MV ;
Ranjekar, PK ;
Gupta, VS .
MOLECULAR BIOLOGY AND EVOLUTION, 2001, 18 (07) :1161-1167
[9]   Equilibrium distributions of microsatellite repeat length resulting from a balance between slippage events and point mutations [J].
Kruglyak, S ;
Durrett, RT ;
Schug, MD ;
Aquadro, CF .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (18) :10774-10778
[10]   Microsatellites within genes: Structure, function, and evolution [J].
Li, YC ;
Korol, AB ;
Fahima, T ;
Nevo, E .
MOLECULAR BIOLOGY AND EVOLUTION, 2004, 21 (06) :991-1007