Laser-Assisted Skin Healing (LASH) in hypertrophic scar revision

被引:17
作者
Capon, Alexandre
Iarmarcovai, Gwen [2 ]
Mordon, Serge [1 ]
机构
[1] Univ Lille Nord France, CHRU, INSERM, U703, Lille, France
[2] APHM, Marseille, France
关键词
Heat; hypertrophic; laser; scar prevention; wound healing; PULSED DYE-LASER; HEAT-SHOCK PROTEINS; SURGICAL SCARS; SUTURE REMOVAL; EXPRESSION; MANAGEMENT; PREVENTION; THERAPIES; KELOIDS; SYSTEM;
D O I
10.3109/14764170903352878
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100227 [皮肤病学];
摘要
Laser-Assisted Skin Healing (LASH) is based on the therapeutic effects of controlled thermal post-conditioning. The authors have previously demonstrated on humans that an 810-nm diode-laser system could assist wound closure leading to an improvement of wound healing with a resulting indiscernible scar. A 47-year-old woman (skin type II), who developed systematically hypertrophic scars after surgery, was enrolled for a hypertrophic scar revision. Excess scar tissue was removed. Immediately after the conventional closure of the incision, laser irradiation (120 J/cm(2)) using a 0.8 cm(2) spot size (rectangular spot, length = 20 mm, width = 4 mm) was applied. Topical silicone gel sheeting (Cerederm (R)) was applied for 2 months afterwards to prevent a thick scar from reforming. No complications occurred during the course of this study. No recurrence of hypertrophic scarring was noticed 6 months after scar revision. This study reports, for the first time, the possibility of improving the appearance of hypertrophic scarring in scar revision by altering through thermal stress the wound-healing process. Since the appropriate initial management of wounds is of importance, the LASH technique could be offered as a new approach to prevent hypertrophic scarring.
引用
收藏
页码:220 / 223
页数:4
相关论文
共 28 条
[1]
Clinical effect of a single pulsed dye laser treatment of fresh surgical scars: Randomized controlled trial [J].
Alam, M ;
Pon, K ;
VAN Laborde, S ;
Kaminer, MS ;
Arndt, KA ;
Dover, JS .
DERMATOLOGIC SURGERY, 2006, 32 (01) :21-25
[2]
Laser scar revision: A review [J].
Alster, Tina ;
Zaulyanov-Scanlon, Larissa .
DERMATOLOGIC SURGERY, 2007, 33 (02) :131-140
[3]
Heat Shock Proteins in Diabetes and Wound Healing [J].
Atalay, Mustafa ;
Oksala, Niku ;
Lappalainen, Jani ;
Laaksonen, David E. ;
Sen, Chandan K. ;
Roy, Sashwati .
CURRENT PROTEIN & PEPTIDE SCIENCE, 2009, 10 (01) :85-95
[4]
Nonsurgical management of hypertrophic scars: Evidence-based therapies, standard practices, and emerging methods [J].
Atiyeh, Bishara S. .
AESTHETIC PLASTIC SURGERY, 2007, 31 (05) :468-492
[5]
Heat shock protein interactions with the glucocorticoid receptor [J].
Bertorelli, G ;
Bocchino, V ;
Olivieri, D .
PULMONARY PHARMACOLOGY & THERAPEUTICS, 1998, 11 (01) :7-12
[6]
Laser treatment of keloids and hypertrophic scars [J].
Bouzari, Navid ;
Davis, Stephen C. ;
Nouri, Keyvan .
INTERNATIONAL JOURNAL OF DERMATOLOGY, 2007, 46 (01) :80-88
[7]
Can thermal lasers promote skin wound healing? [J].
Capon, A ;
Mordon, S .
AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2003, 4 (01) :1-12
[8]
Laser assisted skin closure (LASC) by using a 815-nm diode-laser system accelerates and improves wound healing [J].
Capon, A ;
Souil, E ;
Gauthier, B ;
Sumian, C ;
Bachelet, M ;
Buys, B ;
Polla, BS ;
Mordon, S .
LASERS IN SURGERY AND MEDICINE, 2001, 28 (02) :168-175
[9]
Sear prevention by laser-assisted scar healing (LASH): A pilot study using an 810-nm diode-laser system [J].
Capon, Alexandre C. ;
Gosse, Alban R. ;
Iarmarcovai, Gwen N. K. ;
Cornil, Alain H. ;
Mordon, Serge R. .
LASERS IN SURGERY AND MEDICINE, 2008, 40 (07) :443-445
[10]
Fetal wound healing [J].
Colwell, AS ;
Longaker, MT ;
Lorenz, HP .
FRONTIERS IN BIOSCIENCE-LANDMARK, 2003, 8 :S1240-S1248