A safe and reliable procedure for the iododeamination of aromatic and heteroaromatic amines in a continuous flow reactor

被引：42

作者：

Malet-Sanz, Laia ^{[1
]}

Madrzak, Julia ^{[1
]}

Holvey, Rhian S. ^{[1
]}

Underwood, Toby ^{[1
]}

机构：

[1] Pfizer Global Res & Dev, Res Chem, Sandwich CT13 9NJ, Kent, England

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 52期

关键词：

Iododeamination; Diazo compounds; Flow chemistry; Alkyl nitrites; Continuous flow; MICROREACTOR TECHNOLOGY; SANDMEYER REACTION; ARYL HALIDES; CHEMISTRY; NITRITE; DIAZOTIZATION; DEAMINATION; ARYLAMINES; GENERATION; RADICALS;

D O I：

10.1016/j.tetlet.2009.10.007

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A method for the safe and reliable iododeamination of aromatic and heteroaromatic amines under copper-free conditions is described and its scope is evaluated. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：7263 / 7267

页数：5

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