High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

被引：918

作者：

Rodríguez, CI

Buchholz, F

Galloway, J

Sequerra, R

Kasper, J

Ayala, R

Stewart, AF

Dymecki, SM ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Dept Genet, Boston, MA 02115 USA

[2] Univ Calif San Francisco, Hooper Fdn, San Francisco, CA 94143 USA

[3] European Mol Biol Lab, Gene Express Program, D-69117 Heidelberg, Germany

来源：

NATURE GENETICS | 2000年 / 25卷 / 02期

关键词：

D O I：

10.1038/75973

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页码：139 / 140

页数：2

共 12 条

[1] SITE-SPECIFIC RECOMBINATION OF A TRANSGENE IN FERTILIZED-EGGS BY TRANSIENT EXPRESSION OF CRE RECOMBINASE [J].

ARAKI, K ;

ARAKI, M ;

MIYAZAKI, J ;

VASSALLI, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (01) :160-164

[2] Different thermostabilities of FLP and Cre recombinases: Implications for applied site-specific recombination [J].

Buchholz, F ;

Ringrose, L ;

Angrand, PO ;

Rossi, F ;

Stewart, AF .

NUCLEIC ACIDS RESEARCH, 1996, 24 (21) :4256-4262

[3] Improved properties of FLP recombinase evolved by cycling mutagenesis [J].

Buchholz, F ;

Angrand, PO ;

Stewart, AF .

NATURE BIOTECHNOLOGY, 1998, 16 (07) :657-662

[4] A modular set of Flp, FRT and lacZ fusion vectors for manipulating genes by site-specific recombination [J].

Dymecki, SM .

GENE, 1996, 171 (02) :197-201

[5] Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice [J].

Dymecki, SM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (12) :6191-6196

[6]

DYMECKI SM, 2000, GENE TARGETING PRACT, P37

[7] A UBIQUITOUS MAMMALIAN EXPRESSION VECTOR, PHMG, BASED ON A HOUSEKEEPING GENE PROMOTER [J].

GAUTIER, C ;

MEHTALI, M ;

LATHE, R .

NUCLEIC ACIDS RESEARCH, 1989, 17 (20) :8389-8389

[8] SITE-SPECIFIC RECOMBINASES - TOOLS FOR GENOME ENGINEERING [J].

KILBY, NJ ;

SNAITH, MR ;

MURRAY, JAH .

TRENDS IN GENETICS, 1993, 9 (12) :413-421

[9] Z/AP, a double reporter for Cre-mediated recombination [J].

Lobe, CG ;

Koop, KE ;

Kreppner, W ;

Lomeli, H ;

Gertsenstein, M ;

Nagy, A .

DEVELOPMENTAL BIOLOGY, 1999, 208 (02) :281-292

[10] An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination [J].

Meyers, EN ;

Lewandoski, M ;

Martin, GR .

NATURE GENETICS, 1998, 18 (02) :136-141

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