Acute stroke imaging research roadmap

被引：182

作者：

Wintermark, Max ^{[1
]}

Albers, Gregory W. ^{[2
]}

Alexandrov, Andrei V. ^{[3
]}

Alger, Jeffry R. ^{[4
]}

Bammer, Roland ^{[2
]}

Baron, Jean-Claude ^{[5
]}

Davis, Stephen ^{[6
]}

Demaerschalk, Bart M. ^{[7
]}

Derdeyn, Colin P. ^{[8
]}

Donnan, Geoffrey A. ^{[9
]}

Eastwood, James D. ^{[10
]}

Fiebach, Jochen B. ^{[11
]}

Fisher, Marc ^{[12
]}

Furie, Karen L. ^{[13
]}

Goldmakher, Gregory V. ^{[13
]}

Hacke, Werner ^{[14
]}

Kidwell, Chelsea S. ^{[15
]}

Kloska, Stephan P. ^{[16
]}

Koehrmann, Martin ^{[17
]}

Koroshetz, Walter ^{[18
]}

Lee, Ting-Yim

Lees, Kennedy R. ^{[19
]}

Lev, Michael H. ^{[13
]}

Liebeskind, David S. ^{[20
]}

Ostergaard, Leif ^{[21
]}

Powers, William J. ^{[22
]}

Provenzale, James ^{[10
]}

Schellinger, Peter ^{[23
]}

Silbergleit, Robert ^{[24
]}

Sorensen, Alma Gregory ^{[13
]}

Wardlaw, Joanna ^{[25
]}

Warach, Steven ^{[18
]}

机构：

[1] Univ Calif San Francisco, Dept Radiol, Neuroradiol Sect, San Francisco, CA 94143 USA

[2] Stanford Univ, Palo Alto, CA USA

[3] Univ Alabama, Comprehens Stroke Ctr, Birmingham, AL USA

[4] Univ Calif Los Angeles, Los Angeles, CA USA

[5] Addenbrookes Hosp, Dept Neurol, Cambridge, England

[6] Univ Melbourne, Royal Melbourne Hosp, Dept Neurol, Parkville, Vic 3052, Australia

[7] Mayo Clin, Phoenix, AZ USA

[8] Washington Univ, St Louis, MO USA

[9] Univ Melbourne, Natl Stroke Res Inst, Parkville, Vic 3052, Australia

[10] Duke Univ, Med Ctr, Dept Radiol, Durham, NC 27710 USA

[11] Charite Univ Hosp & Berlin, NeuroImaging Ctr BNIC, Berlin, Germany

[12] Univ Massachusetts, Sch Med, Worcester, MA 01605 USA

[13] Massachusetts Gen Hosp, Boston, MA 02114 USA

[14] Univ Heidelberg, D-6900 Heidelberg, Germany

[15] Georgetown Univ, Washington Hosp Ctr, Washington, DC USA

[16] Univ Munster, Dept Clin Radiol, Munster, Germany

[17] Univ Clin, Dept Neurol, Erlangen, Germany

[18] Natl Inst Neurol Disorders & Stroke, Bethesda, MD USA

[19] Univ Glasgow, Western Infirm, Univ Dept Med & Therapeut, Glasgow G12 8QQ, Lanark, Scotland

[20] Univ Calif Los Angeles, Los Angeles Stroke Ctr, Los Angeles, CA 90024 USA

[21] Ctr Funct Integrat Neurosci, Dept Neuroradiol, Aarhus, Denmark

[22] Univ N Carolina, Dept Neurol, Chapel Hill, NC USA

[23] Univ Clin, Dept Neurol, Erlangen, Germany

[24] Univ Michigan, Ann Arbor, MI 48109 USA

[25] Western Gen Hosp, Edinburgh EH4 2XU, Midlothian, Scotland

来源：

STROKE | 2008年 / 39卷 / 05期

关键词：

acute stroke; CT; magnetic resonance; outcomes; thrombolysis; perfusion imaging;

D O I：

10.1161/STROKEAHA.107.512319

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The recent "Advanced Neuroimaging for Acute Stroke Treatment" meeting on September 7 and 8, 2007 in Washington DC, brought together stroke neurologists, neuroradiologists, emergency physicians, neuroimaging research scientists, members of the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Biomedical Imaging and Bioengineering (NIBIB), industry representatives, and members of the US Food and Drug Administration (FDA) to discuss the role of advanced neuroimaging in acute stroke treatment. The goals of the meeting were to assess state-of-the-art practice in terms of acute stroke imaging research and to propose specific recommendations regarding: (1) the standardization of perfusion and penumbral imaging techniques, (2) the validation of the accuracy and clinical utility of imaging markers of the ischemic penumbra, (3) the validation of imaging biomarkers relevant to clinical outcomes, and (4) the creation of a central repository to achieve these goals. The present article summarizes these recommendations and examines practical steps to achieve them.

引用

页码：1621 / 1628

页数：8