Sulfonylation in the rearrangement of an N-phosphinoyl-O-sulfonylhydroxylamine: Demonstration of a phosphonamidic-sulfonic anhydride intermediate and O-18-labelling evidence on how it may be formed

被引：3

作者：

Harger, MJP

机构：

[1] Department of Chemistry, The University, Leicester

来源：

CHEMICAL COMMUNICATIONS | 1997年 / 04期

关键词：

D O I：

10.1039/a608043j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The rearrangement reaction of R(Ph)P(O)NHOSO(2)Bn (R = PhMeCH) (57% enriched with one O-18 atom in the SO2 group) with Bu(t)NH(2) in CH2Cl2 gives the sulfonamide BnSO(2)NHBu(t) (43.7% enriched with one O-18 atom) as one of the products; this indicates a phosphonamidic-sulfonic anhydride intermediate [R(BnSO(2)O)P(O)NHPh], formed with partial equilibration of the sulfonate oxygen atoms and attacked (in part) at the sulfonyl group.

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页码：403 / 404

页数：2

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