Overview of studies on metabolic and vascular regulatory changes in early diabetic retinopathy

被引：22

作者：

Alder, VA

Su, EN

Yu, DY

Cringle, S

Yu, P

机构：

[1] Univ Western Australia, Lions Eye Inst, Nedlands, WA 6009, Australia

[2] Univ Western Australia, Ctr Ophthalmol & Visual Sci, Nedlands, WA 6009, Australia

来源：

AUSTRALIAN AND NEW ZEALAND JOURNAL OF OPHTHALMOLOGY | 1998年 / 26卷 / 02期

关键词：

blood flow; diabetic retinopathy; functional changes; oxygen; retinal vasculature;

D O I：

10.1111/j.1442-9071.1998.tb01530.x

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

The present review provides an overview of recent research describing functional changes to the retinal vasculature in very early diabetes. The research focuses on the streptozotocin rat model after 4-6 weeks of induced diabetes and describes functional changes to retinal blood flow, vascular control and retinal oxygenation, as well as a strong vasodilatory response to insulin in the retinal vasculature. The review raises the question of whether choroid dysfunction is also a feature of diabetic retinopathy.

引用

页码：141 / 148

页数：8

共 26 条

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