A new dynamic resolution strategy for asymmetric synthesis

被引：41

作者：

Caddick, S

Jenkins, K

机构：

[1] Sch. of Chem. and Molecular Sciences, University of Sussex, Falmer, Brighton

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 08期

关键词：

D O I：

10.1016/0040-4039(95)02379-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two different and complementary auxiliary based dynamic resolution processes have been developed; the use of crystallisation induced dynamic resolution and/or dynamic kinetic resolution enables the preparation of either enantiomeric product using a single chiral auxiliary as illustrated in the preparation of D or L-alanine derivatives.

引用

页码：1301 / 1304

页数：4

共 16 条

[1] [Anonymous], 1981, ENANTIOMERS RACEMATE
[2] CLOSE WJ, 1950, J ORG CHEM, V15, P1131
[3] ELIEL EL, 1993, STEREOCHEMISTRY ORGA, P297
[4] HARRIS MM, 1958, PROGR STEREOCHEM, V2, P157
[5] REACTION OF (R)-PANTOLACTONE ESTERS OF ALPHA-BROMOACIDS WITH AMINES - A REMARKABLE SYNTHESIS OF OPTICALLY-ACTIVE ALPHA-AMINO ESTERS
KOH, K
BEN, RN
DURST, T
[J]. TETRAHEDRON LETTERS, 1993, 34 (28) : 4473 - 4476
[6] STEREOSELECTIVE S(N)2 REACTIONS OF THE (R)-PANTOLACTONE ESTER OF RACEMIC ALPHA-HALO CARBOXYLIC-ACIDS WITH ARYLOXIDES - A SYNTHESIS OF (S)-2-ARYLOXY AND (S)-2-HYDROXY ACIDS
KOH, K
DURST, T
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (16) : 4683 - 4686
[7] DYNAMIC KINETIC RESOLUTION UTILIZING A CHIRAL AUXILIARY BY STEREOSELECTIVE SN2 ALKYLATION WITH MALONIC ESTER ENOLATE
KUBO, A
TAKAHASHI, M
KUBOTA, H
NUNAMI, KI
[J]. TETRAHEDRON LETTERS, 1995, 36 (35) : 6251 - 6252
[8] STEREOSPECIFIC AMINATION BY DYNAMIC KINETIC RESOLUTION UTILIZING 2-OXOIMIDAZOLIDINE-4-CARBOXYLATE AS A NOVEL CHIRAL AUXILIARY
KUBOTA, H
KUBO, A
TAKAHASHI, M
SHIMIZU, R
DATE, T
OKAMURA, K
NUNAMI, K
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (21) : 6776 - 6784
[9] STEREOSELECTIVE ORGANIC-SYNTHESIS VIA DYNAMIC KINETIC RESOLUTION
NOYORI, R
TOKUNAGA, M
KITAMURA, M
[J]. BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1995, 68 (01) : 36 - 55
[10] OMEARA JA, 1995, TETRAHEDRON LETT, V36, P5096

← 1 2 →