Neurological potassium channelopathies

被引：29

作者：

Benatar, M ^{[1
]}

机构：

[1] Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA

来源：

QJM-MONTHLY JOURNAL OF THE ASSOCIATION OF PHYSICIANS | 2000年 / 93卷 / 12期

关键词：

D O I：

10.1093/qjmed/93.12.787

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Potassium channel dysfunction has been implicated in a variety of genetic and acquired neurological disorders that are collectively referred to as the potassium channelopathies. These include acquired neuromyotonia, episodic ataxia type-1, hereditary deafness syndromes, benign familial neonatal convulsions and hypokalaemic periodic paralysis. Insight into potassium channel structure and function is crucial to understanding the pathophysiology of these conditions. This article describes potassium channel structure and function and then outlines what is known about the immunology and genetics of the neurological potassium channelopathies.

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页码：787 / 797

页数：11

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