Immunohistochemical detection of galectin-3 in canine gastric carcinomas

被引：15

作者：

Woo, HJ

Joo, HG

Song, SW

Sohn, YS

Chae, C ^{[1
]}

机构：

[1] Seoul Natl Univ, Coll Vet Med, Dept Vet Pathol, Suwon 441744, Kyounggi Do, South Korea

[2] Seoul Natl Univ, Coll Vet Med, Dept Immunol, Suwon 441744, Kyounggi Do, South Korea

[3] Seoul Natl Univ, Coll Vet Med, Dept Immunol, Suwon 441744, Kyounggi Do, South Korea

[4] Seoul Natl Univ, Sch Agr Biotechnol, Suwon 441744, Kyounggi Do, South Korea

来源：

JOURNAL OF COMPARATIVE PATHOLOGY | 2001年 / 124卷 / 2-3期

关键词：

D O I：

10.1053/jcpa.2000.0442

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Galectin-3 was detected immunohistochemically in nine canine gastric carcinomas. In normal gastric tissue adjacent to the neoplasms, the gastric epithelial cells showed faint immunolabelling for galectin-3, but in all the tumours the neoplastic cells showed moderate to strong immunolabelling. Galectin-3 was localized in the cytoplasm of the normal mucosal cells, whereas it was found in both the cytoplasm and the nucleus of the neoplastic cells. Positive cells typically exhibited dark brown coloration of the nucleus or cytoplasm, without background labelling. The results suggest that galactin-3 has a pathophysiological role in canine gastric carcinoma. (C) 2001 Harcourt Publishers Ltd.

引用

页码：216 / 218

页数：3

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