Stereocontrolled synthesis of 5-(1′-hydroxyalkyl)-3-methylidenetetrahydro-2-furanones

被引：13

作者：

Janecki, T ^{[1
]}

Blaszczyk, E ^{[1
]}

机构：

[1] Lodz Tech Univ, Inst Organ Chem, PL-90924 Lodz, Poland

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 15期

关键词：

Horner-Wadsworth-Emmons olefination; 2-furanones; diastereoselection; enantioselection;

D O I：

10.1016/S0040-4039(01)00316-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Diastereo- and enantioselective synthesis of 5-(1 ' -hydroxyalkyl)-3-methylidenetetrahydro-2-furanones from 2-diethoxyphosphoryl-4-alkenoic acids or 2-diethoxyphosphoryl-4-alkenoates was readily accomplished using novel methodology involving syn- or anti-dihydroxylation procedures combined with Horner-Wadsworth-Emmons olefination techniques. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：2919 / 2922

页数：4

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