The release of kininase from rat isolated hearts during myocardial ischaemia

被引：6

作者：

Ahmad, M ^{[1
]}

Zeitlin, IJ ^{[1
]}

Parratt, JR ^{[1
]}

机构：

[1] UNIV STRATHCLYDE,DEPT PHYSIOL & PHARMACOL,GLASGOW G1 1XW,LANARK,SCOTLAND

来源：

IMMUNOPHARMACOLOGY | 1996年 / 33卷 / 1-3期

关键词：

myocardial ischaemia; kininase; bradykinin;

D O I：

10.1016/0162-3109(96)00047-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

BK destroying activity was observed in rat isolated heart perfusates. BK was optimally degraded at pH 8.4 in rat heart. The results indicated that myocardial kinin degradation was due to ACE and a serine protease. These results suggest that bradykinin may have some cardioprotective role during myocardial ischaemia at acidic pH.

引用

页码：299 / 300

页数：2

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