Moving forward in human mammary stem cell biology and breast cancer prognostication using ALDH1

被引：133

作者：

Balicki, Danuta

机构：

[1] Univ Montreal, Hotel Dieu, Ctr Hosp, Dept Med, Montreal, PQ H2W 1T7, Canada

[2] Univ Montreal, Hotel Dieu, Ctr Hosp, Res Ctr, Montreal, PQ H2W 1T7, Canada

[3] Univ Montreal, Dept Med, Montreal, PQ H3C 3J7, Canada

[4] Ville Marie Multidisciplinary Breast Ctr, Breast Canc Risk Assessment Clin, Montreal, PQ H3G 1L5, Canada

来源：

CELL STEM CELL | 2007年 / 1卷 / 05期

关键词：

D O I：

10.1016/j.stem.2007.10.015

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

In this issue of Cell Stem Cell, the seminal work of Ginestier et al. (2007) elegantly demonstrates that aldehyde dehydrogenase 1 (ALDH1) facilitates the identification and isolation of normal and malignant human mammary stem cells in vitro, in vivo, and in situ in fixed tissues.

引用

收藏

页码：485 / 487

页数：3

相关论文

共 10 条

[1]

Prospective identification of tumorigenic breast cancer cells [J].

Al-Hajj, M ;

Wicha, MS ;

Benito-Hernandez, A ;

Morrison, SJ ;

Clarke, MF .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (07) :3983-3988

[2]

BALLICKI D, 2007, PHARMACOGENETICS BRE

[3]

BALLICKI D, 2007, IN PRESS CANC STEM C

[4]

Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells [J].

Chute, John P. ;

Muramoto, Garrett G. ;

Whitesides, John ;

Colvin, Michael ;

Safi, Rachid ;

Chao, Nelson J. ;

McDonnell, Donald P. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (31) :11707-11712

[5]

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome [J].

Ginestier, Christophe ;

Hur, Min Hee ;

Charafe-Jauffret, Emmanuelle ;

Monville, Florence ;

Dutcher, Julie ;

Brown, Marty ;

Jacquemier, Jocelyne ;

Viens, Patrice ;

Kleer, Celina G. ;

Liu, Suling ;

Schott, Anne ;

Hayes, Dan ;

Birnbaum, Daniel ;

Wicha, Max S. ;

Dontu, Gabriela .

CELL STEM CELL, 2007, 1 (05) :555-567

[6]

SP analysis may be used to identify cancer stem cell populations [J].

Hadnagy, Annamaria ;

Gaboury, Louis ;

Beaulieu, Raymond ;

Balicki, Danuta .

EXPERIMENTAL CELL RESEARCH, 2006, 312 (19) :3701-3710

[7]

Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity [J].

Hess, DA ;

Meyerrose, TE ;

Wirthlin, L ;

Craft, TP ;

Herrbrich, PE ;

Creer, MH ;

Nolta, JA .

BLOOD, 2004, 104 (06) :1648-1655

[8]

The activity of class I, II, III, and IV of alcohol dehydrogenase isoenzymes and aldehyde dehydrogenase in pancreatic cancer [J].

Jelski, Wojciech ;

Chrostek, Lech ;

Szmitkowski, Maciej .

PANCREAS, 2007, 35 (02) :142-146

[9]

Mesenchymal stem cells within tumour stroma promote breast cancer metastasis [J].

Karnoub, Antoine E. ;

Dash, Ajeeta B. ;

Vo, Annie P. ;

Sullivan, Andrew ;

Brooks, Mary W. ;

Bell, George W. ;

Richardson, Andrea L. ;

Polyak, Kornelia ;

Tubo, Ross ;

Weinberg, Robert A. .

NATURE, 2007, 449 (7162) :557-U4

[10]

Susceptibility to lung cancer and genetic polymorphisms in the alcohol metabolite-related enzymes alcohol dehydrogenase 3, aldehyde dehydrogenase 2, and cytochrome P450 2E1 in the Japanese population [J].

Minegishi, Yuji ;

Tsukino, Hiromasa ;

Muto, Manabu ;

Goto, Koichi ;

Gernma, Akihiko ;

Tsugane, Shoichiro ;

Kudoh, Shoji ;

Nishiwaki, Yutaka ;

Esumi, Hiroyasu .

CANCER, 2007, 110 (02) :353-362