Triterpene saponins from the roots of Achyranthes bidentata

被引：22

作者：

Marouf, A

Desbene, S

Khanh, TC

Wagner, H

Correia, M

Chauffert, B

Lacaille-Dubois, MA

机构：

[1] Univ Bourgogne, Fac Pharm, Unite Mol Interet Biol, Lab Pharmacognosie, F-21079 Dijon, France

[2] Univ Oran, Fac Sci, Dept Biol, Oran, Algeria

[3] Univ Hanoi, Hanoi Coll Pharm, Dept Chem, Hanoi, Vietnam

[4] Univ Munich, Inst Pharmaceut Biol, D-8000 Munich, Germany

[5] Univ Bourgogne, Fac Med, INSERM, U517,Unite Mort Cellulaire & Canc, Dijon, France

来源：

PHARMACEUTICAL BIOLOGY | 2001年 / 39卷 / 04期

关键词：

Achyranthes bibentata; Amaranthaceae saponins; immunology;

D O I：

10.1076/phbi.39.4.263.5908

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three saponins, oleanolic acid-28-O-beta -D-glucopyranoside (1), chikusetsusaponin V (2), and 3-O-beta -D-glucopyranosyloleanolic acid-28-O-beta -D-glucopyranoside (3) were isolated from the roots of Achyranthes bidentata Blume (Amaranthaceae). No activity was shown in the granulocyte phagocytosis test nor in the test of the potentiation of the cytotoxicity of cisplatin in human colon cancer cells. This is the first report of compounds 1, 2 and 3 isolated from Achyranthes species. Furthermore, the NMR data of 2 completed the partially published data.

引用

页码：263 / 267

页数：5

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