Genes and subtypes of schizophrenia

被引：25

作者：

Mirnics, K

Lewis, DA

机构：

[1] Univ Pittsburgh, Sch Med, Dept Psychiat, Pittsburgh, PA 15261 USA

[2] Univ Pittsburgh, Sch Med, Dept Neurobiol, Pittsburgh, PA 15261 USA

[3] Univ Pittsburgh, Sch Med, Dept Neurosci, Pittsburgh, PA 15261 USA

来源：

TRENDS IN MOLECULAR MEDICINE | 2001年 / 7卷 / 07期

关键词：

D O I：

10.1016/S1471-4914(01)02067-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The complex heterogeneity of schizophrenia renders identification of a specific etiology extremely difficult. Nevertheless, there is strong heritability in affected families, and linkage has been demonstrated at several loci. A recent study has bypassed some of these complexities, with the identification of a gene mutation in some individuals with a specific subtype of schizophrenia, periodic catatonia - and points to new strategies for the analysis of other polygenic neurological disorders.

引用

页码：281 / 283

页数：3

共 26 条

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