Successful treatment of metronidazole- and albendazole-resistant giardiasis with nitazoxanide in a patient with acquired immunodeficiency syndrome

被引：68

作者：

Abboud, P

Lemée, V

Gargala, G

Brasseur, P

Ballet, JJ

Borsa-Lebas, F

Caron, F

Favennec, L ^{[1
]}

机构：

[1] CHU Ch Nicolle, Parasitol Lab, ADEN, F-76031 Rouen, France

[2] Ctr Hosp Univ Ch Nicolle, Serv Malad Infect, F-76031 Rouen, France

[3] CHU Clemenceau, Immunol Lab, Caen, France

来源：

CLINICAL INFECTIOUS DISEASES | 2001年 / 32卷 / 12期

关键词：

D O I：

10.1086/320751

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A case of metronidazole-and albendazole-resistant giardiasis in a patient with the acquired immunodeficiency syndrome was successfully treated with nitazoxanide (1.5 g twice a day for 30 days). Animal studies and in vitro assays showed that the isolate was resistant to both metronidazole and albendazole and susceptible to nitazoxanide.

引用

页码：1792 / 1794

页数：3

共 10 条

[1] Drug resistance among malaria and other parasites [J].

Barat, LM ;

Bloland, PB .

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 1997, 11 (04) :969-&

[2] Nitazoxanide for the treatment of intestinal protozoan and helminthic infections in Mexico [J].

Cabello, RR ;

Guerrero, LR ;

Garcia, MDM ;

Cruz, AG .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1997, 91 (06) :701-703

[3]

Cacopardo B, 1995, Clin Ter, V146, P761

[4]

CDC (Cent. Dis. Control Prev.), 1992, MMWR RECOMM REP, V41, P1

[5]

COTTE L, 1993, J ACQ IMMUN DEF SYND, V6, P1024

[6] A NEW SCREENING ASSAY FOR ANTIGIARDIAL COMPOUNDS - EFFECTS OF VARIOUS DRUGS ON THE ADHERENCE OF GIARDIA-DUODENALIS TO CACO2 CELLS [J].

FAVENNEC, L ;

CHOCHILLON, C ;

MAGNE, D ;

MEILLET, D ;

RAICHVARG, D ;

SAVEL, J ;

GOBERT, JG .

PARASITOLOGY RESEARCH, 1992, 78 (01) :80-81

[7] Metronidazole and albendazole susceptibility of 11 clinical isolates of Giardia duodenalis from France [J].

Lemée, V ;

Zaharia, I ;

Nevez, G ;

Rabodonirina, M ;

Brasseur, P ;

Ballet, JJ ;

Favennec, L .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2000, 46 (05) :819-821

[8]

Rodriguez-Garcia R, 1999, Rev Gastroenterol Mex, V64, P122

[9]

*ROM LAB, 2000, NIT INV BROCH

[10]

Stockis A, 1996, INT J CLIN PHARM TH, V34, P349

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