Cytotoxic chromenes from Myriactis humilis

被引:22
作者
Chen, JJ [1 ]
Duh, CY
Chen, IS
机构
[1] Tajen Inst Technol, Dept Pharm, Pingtung 907, Taiwan
[2] Natl Sun Yat Sen Univ, Inst Marine Resources, Kaohsiung 80424, Taiwan
[3] Kaohsiung Med Univ, Sch Pharm, Kaohsiung, Taiwan
关键词
D O I
10.1055/s-2005-864107
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Two new chromenes, myriachromene and 2,2-dimethyl-6,7-methylenedioxy-2H-chromene, together with ten known compounds including alpha-tocopherylquinone, alpha-tocopherol acetate, diphenyl sulfone, beta-carotene, chondrillasterol, beta-sitosterol, beta-sitostenone, vanillin, and vanillic acid were isolated from the whole plant of Myriactis humilis. The structures of these new compounds were determined through spectral analyses. Among the isolates, four compounds exhibited cytotoxicity (ED50 values < 4 mu g/mL) against P-388 or HT-29 cell lines in vitro.
引用
收藏
页码:370 / 372
页数:3
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