The search for new cardiovascular biomarkers

被引：252

作者：

Gerszten, Robert E. ^{[1
,2
]}

Wang, Thomas J. ^{[1
]}

机构：

[1] Massachusetts Gen Hosp, Div Cardiol, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Ctr Immunol & Inflammatory Dis, Charlestown, MA 02129 USA

来源：

NATURE | 2008年 / 451卷 / 7181期

关键词：

D O I：

10.1038/nature06802

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Despite considerable advances in the treatment of cardiovascular disease, it remains the leading cause of death in developed countries. Assessment of classic cardiovascular risk factors-including high blood pressure, diabetes and smoking-has a central role in disease prevention. However, many individuals with coronary heart disease (a narrowing of the blood vessels that supply the heart) have only one, or none, of the classic risk factors. Thus, new biomarkers are needed to augment the information obtained from traditional indicators and to illuminate disease mechanisms.

引用

页码：949 / 952

页数：4

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