Population genomics: Linkage disequilibrium holds the key

被引：99

作者：

Goldstein, DB

Weale, ME

机构：

[1] UCL, Galton Lab, Dept Biol, London NW1 2HE, England

[2] Genost Ltd, London WC1A 2HN, England

来源：

CURRENT BIOLOGY | 2001年 / 11卷 / 14期

关键词：

D O I：

10.1016/S0960-9822(01)00348-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Current efforts to find disease-causing genes depend on patterns of linkage disequilibrium in human populations. Recent work has shown that linkage disequilibrium can extend over much larger genomic regions than expected, and that the patterns of linkage disequilibrium can differ markedly among populations.

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收藏

页码：R576 / R579

页数：4

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