Cerium oxide nanoparticles scavenge nitric oxide radical (•NO)

被引：209

作者：

Dowding, Janet M. ^{[1
]}

Dosani, Talib ^{[1
]}

Kumar, Amit ^{[2
,3
]}

Seal, Sudipta ^{[2
,3
]}

Self, William T. ^{[1
]}

机构：

[1] Univ Cent Florida, Coll Med, Burnett Sch Biomed Sci, Orlando, FL 32816 USA

[2] Univ Cent Florida, Nanosci & Technol Ctr, Orlando, FL 32816 USA

[3] Univ Cent Florida, Adv Mat Proc & Anal Ctr, Orlando, FL 32816 USA

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 40期

关键词：

NO; COMPLEXES; MODEL; HEMOGLOBIN; MECHANISMS; DISEASE; HEALTH;

D O I：

10.1039/c2cc30485f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this study we have obtained evidence that cerium oxide nanoparticles (CeO2 NPs) are able to scavenge nitric oxide radical. Surprisingly, this activity is present in CeO2 NPs with a lower level of cerium in the 3+ state (CeO2 NPs with low 3+/4+ ratio and therefore a reduced number of oxygen vacancies), in contrast to the superoxide scavenging properties which are correlated with an increased level of cerium in the 3+ state (CeO2 NPs with high 3+/4+ ratio and therefore an increased number of oxygen vacancies).

引用

页码：4896 / 4898

页数：3

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