FET-1:: a novel W-linked, female specific gene up-regulated in the embryonic chicken ovary

被引:36
作者
Reed, Kirsty J.
Sinclair, Andrew H. [1 ]
机构
[1] Royal Childrens Hosp, Murdoch Childrens Res Inst, Melbourne, Vic, Australia
[2] Univ Melbourne, Dept Paediat, Melbourne, Vic, Australia
基金
英国医学研究理事会;
关键词
sex determination; female gonad development; ovary development; W chromosome;
D O I
10.1016/S0925-4773(03)00097-2
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
A differential expression screen for sex-determining genes in the embryonic chicken gonad revealed a novel gene called Female Expressed Transcript 1 ( FET-1). Fluorescent in situ hybridization analysis mapped FET-1 to the female specific W chromosome. Whole mount in situ hybridization showed that FET-1 expression was restricted to females and up-regulated in the cortex of the left gonad during the sex-determining period. Female specific expression was also observed in the embryonic caudal somites, neural tube and waste collection ducts. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:S87 / S90
页数:4
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