Chlamydia pneumoniae is a common respiratory pathogen that is now being implicated in a number of chronic diseases. That the organism can infect vascular endothelium, macrophages and smooth muscle cells suggests that it may play a role in many systemic diseases. The present review focuses on the possibility that the central nervous system can also be a target of this agent. The tropism of C. pneumoniae to the neural tissue suggests it may play a role in diverse neurologic diseases, including Alzheimer's disease, multiple sclerosis and giant-cell arteritis. Curr Opin Neurol 14:355-359. (C) 2001 Lippincott Williams & Wilkins.
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Hop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, FranceHop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, France
Guglielminotti, J
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Lellouche, N
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Hop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, FranceHop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, France
Lellouche, N
;
Maury, E
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Hop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, FranceHop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, France
Maury, E
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Alzieu, M
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Hop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, FranceHop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, France
Alzieu, M
;
Guidet, B
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Hop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, FranceHop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, France
Guidet, B
;
Offenstadt, G
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Hop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, FranceHop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, France
机构:
Hop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, FranceHop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, France
Guglielminotti, J
;
Lellouche, N
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机构:
Hop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, FranceHop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, France
Lellouche, N
;
Maury, E
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机构:
Hop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, FranceHop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, France
Maury, E
;
Alzieu, M
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机构:
Hop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, FranceHop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, France
Alzieu, M
;
Guidet, B
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Hop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, FranceHop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, France
Guidet, B
;
Offenstadt, G
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Hop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, FranceHop St Antoine, Serv Reanimat Med, Assistance Publ Hopitaux Paris, F-75571 Paris 12, France