Total synthesis of luotonin A

被引:57
作者
Kelly, TR [1 ]
Chamberland, S [1 ]
Silva, RA [1 ]
机构
[1] Boston Coll, EF Merkert Chem Ctr, Chestnut Hill, MA 02467 USA
关键词
D O I
10.1016/S0040-4039(99)00349-4
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of the cytotoxic alkaloid luotonin A (1), which has been shown to possess antileukemic activity, has been achieved. The key step in the synthesis is a Friedlander condensation between 2-aminobenzaldehyde and dione 5. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:2723 / 2724
页数:2
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