Etanercept improves the health-related quality of life of patients with psoriasis: Results of a phase III randomized clinical trial

被引:69
作者
Feldman, SR
Kimball, AB
Krueger, GG
Woolley, JM
Lalla, D
Jahreis, A
机构
[1] Wake Forest Univ, Bowman Gray Sch Med, Dept Dermatol, Winston Salem, NC 27157 USA
[2] Massachusetts Gen Hosp, Boston, MA 02114 USA
[3] Brigham & Womens Hosp, Boston, MA 02115 USA
[4] Utah Hlth Sci Ctr, Salt Lake City, UT USA
[5] Amgen Inc, Thousand Oaks, CA USA
关键词
D O I
10.1016/j.jaad.2005.06.053
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
In this randomized, double-blind, phase III trial, patients with psoriasis received etanercept for 24 weeks or placebo for 12 weeks followed by etanercept for 12 weeks. At week 12, improvement in Dermatology Life Quality Index was 47% to 61% with etanercept compared with 11% with placebo (P <.0001). Etanercept rapidly and substantially improved patients' health-related quality of life.
引用
收藏
页码:887 / 889
页数:3
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