Multiple sclerosis normal-appearing white matter: Pathology-imaging correlations

被引:223
作者
Moll, Natalia M. [2 ,3 ]
Rietsch, Anna M. [2 ,3 ]
Thomas, Smitha [1 ]
Ransohoff, Amy J. [2 ,3 ]
Lee, Jar-Chi [4 ]
Fox, Robert [5 ]
Chang, Ansi [3 ]
Ransohoff, Richard M. [2 ,3 ,5 ]
Fisher, Elizabeth [1 ]
机构
[1] Cleveland Clin, Lerner Res Inst, Dept Biomed Engn, Cleveland, OH 44195 USA
[2] Cleveland Clin, Lerner Res Inst, Neuroinflammat Res Ctr, Cleveland, OH 44195 USA
[3] Cleveland Clin, Lerner Res Inst, Dept Neurosci, Cleveland, OH 44195 USA
[4] Cleveland Clin, Dept Quantitat Hlth Sci, Cleveland, OH 44195 USA
[5] Cleveland Clin, Mellen Ctr Multiple Sclerosis Treatment & Res, Neurol Inst, Cleveland, OH 44195 USA
关键词
MAGNETIZATION-TRANSFER RATIO; IN-VIVO; CORTICAL DEMYELINATION; INTERFERON BETA-1B; MEDICAL PROGRESS; RETINAL ISCHEMIA; CORPUS-CALLOSUM; OPTIC-NERVE; BRAIN; LESIONS;
D O I
10.1002/ana.22521
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective: The study was undertaken to determine the pathologic basis of subtle abnormalities in magnetization transfer ratio (MTR) and diffusion tensor imaging (DTI) parameters observed in normal-appearing white matter (NAWM) in multiple sclerosis brains.
引用
收藏
页码:764 / 773
页数:10
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