Cell polarity: ROPing the ends together

被引:41
作者
Xu, J [1 ]
Scheres, B [1 ]
机构
[1] Univ Utrecht, Dept Mol Genet, NL-3584 CH Utrecht, Netherlands
关键词
D O I
10.1016/j.pbi.2005.09.003
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Cell polarity plays an important role in plant development, but the mechanisms that first establish polarity cues remain obscure. By contrast, a flurry of information has recently emerged on the elaboration of cell shape from such unknown initial cell-polarity cues. Recent studies suggest that Rho-related GTPases in plants (ROPs), and their effector targets among the ROP-interactive CRIB motif-containing proteins (RICs), mediate two antagonistic pathways that have opposing action on cell polarization. ROP proteins appear to interact directly with upstream regulators of the ARP2/3 complex, which are conserved modulators of the actin cytoskeleton. ROP function is dependent on the class 1 ADP-ribosylation factors (ARFs), which are core components of the vesicle transport machinery that are also involved in the polar localization of PIN-FORMED (PIN) family auxin efflux facilitators.
引用
收藏
页码:613 / 618
页数:6
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