Cyclodextrins as hosts for poorly water-soluble compounds in enzyme catalysis

被引：16

作者：

Bru, R ^{[1
]}

LopezNicolas, JM ^{[1
]}

NunezDelicado, E ^{[1
]}

NortesRuiperez, D ^{[1
]}

SanchezFerrer, A ^{[1
]}

GarciaCarmona, F ^{[1
]}

机构：

[1] UNIV MURCIA,DEPT BIOQUIM & BIOL MOL A,FAC BIOL,E-30001 MURCIA,SPAIN

来源：

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY | 1996年 / 61卷 / 1-2期

关键词：

cyclodextrins; linoleic acid; diethylstilbestrol; cholesterol; lipoxygenase; cholesterol oxidase;

D O I：

10.1007/BF02785701

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The capability of cyclodextrins to enhance greatly the solubility in water of poorly water-soluble substances makes them an ideal alternative for investigating the expression of enzyme activity with such substrates in aqueous solution. This capability is demonstrated by using soybean lipoxygenase with linoleic acid/beta-cyclodextrin and diethylstilbestrol/gamma-cyclodextrin, and cholesterol oxidase with cholesterol/methyl-beta-cyclodextrin.

引用

页码：189 / 198

页数：10

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