Controversies about COVID-19 and anticancer treatment with immune checkpoint inhibitors

被引：165

作者：

Bersanelli, Melissa ^{[1
,2
]}

机构：

[1] Univ Hosp Parma, Med Oncol Unit, Parma, Italy

[2] Univ Parma, Dept Surg & Med, Parma, Italy

来源：

IMMUNOTHERAPY | 2020年 / 12卷 / 05期

关键词：

anti-CTLA-4; anti-PD-1; anti-PD-L1; cancer patients; COVID-19; immune checkpoint inhibitors; immunotherapy; SARS-CoV-2; tocilizumab; viral infection;

D O I：

10.2217/imt-2020-0067

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

Since ICI can restore the immune-competence, if on one hand it can be paradoxically needed to develop the cytokine storm characterizing the acute respiratory distress syndrome (ARDS) phase, on the other hand the epidemiological features of SARS-CoV-2 infection lay for a lower probability to affect these patients compared with their chemo-Treated immune-suppressed counterpart. © 2020 Future Medicine Ltd.

引用

页码：269 / 273

页数：5

共 25 条

[1]

Adhanom Ghebreyesus T, 2020, WHO DIRECTOR GEN OPE

[2]

AIOM (Associazione Italiana di Oncologia Medica), 2020, COM AIOM PER EM COR

[3]

Presumed Asymptomatic Carrier Transmission of COVID-19 [J].

Bai, Yan ;

Yao, Lingsheng ;

Wei, Tao ;

Tian, Fei ;

Jin, Dong-Yan ;

Chen, Lijuan ;

Wang, Meiyun .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (14) :1406-1407

[4]

Immunological insights on influenza infection and vaccination during immune checkpoint blockade in cancer patients [J].

Bersanelli, Melissa ;

Scala, Stefania ;

Affanni, Paola ;

Veronesi, Licia ;

Colucci, Maria Eugenia ;

Banna, Giuseppe Luigi ;

Cortellini, Alessio ;

Liotta, Francesco .

IMMUNOTHERAPY, 2020, 12 (02) :105-110

[5]

INfluenza Vaccine Indication During therapy with Immune checkpoint inhibitors: a transversal challenge. The INVIDIa study [J].

Bersanelli, Melissa ;

Giannarelli, Diana ;

Castrignano, Paola ;

Fornarini, Giuseppe ;

Panni, Stefano ;

Mazzoni, Francesca ;

Tiseo, Marcello ;

Rossetti, Sabrina ;

Gambale, Elisabetta ;

Rossi, Ernesto ;

Papa, Anselmo ;

Cortellini, Alessio ;

Lolli, Cristian ;

Ratta, Raffaele ;

Michiara, Maria ;

Milella, Michele ;

De Luca, Emmanuele ;

Soraru, Mariella ;

Mucciarini, Claudia ;

Atzori, Francesco ;

Banna, Giuseppe L. ;

La Torre, Leonardo ;

Vitale, Maria G. ;

Massari, Francesco ;

Rebuzzi, Sara E. ;

Facchini, Gaetano ;

Schinzari, Giovanni ;

Tomao, Silverio ;

Bui, Simona ;

Vaccaro, Vanja ;

Procopio, Giuseppe ;

De Giorgi, Ugo ;

Santoni, Matteo ;

Ficorella, Corrado ;

Sabbatini, Roberto ;

Maestri, Antonio ;

Natoli, Clara ;

De Tursi, Michele ;

Di Maio, Massimo ;

Rapacchi, Elena ;

Pireddu, Annagrazia ;

Sava, Teodoro ;

Lipari, Helga ;

Comito, Francesca ;

Verzoni, Elena ;

Leonardi, Francesco ;

Buti, Sebastiano .

IMMUNOTHERAPY, 2018, 10 (14) :1229-1239

[6]

Bersanelli M, 2017, WORLD J CLIN ONCOL, V8, P37, DOI 10.5306/wjco.v8.i1.37

[7]

Chen C, 2020, Zhonghua Shao Shang Za Zhi, V36, P471, DOI 10.3760/cma.j.cn501120-20200224-00088

[8]

Clinical Characteristics and Treatment of Immune-Related Adverse Events of Immune Checkpoint Inhibitors [J].

Choi, Juwhan ;

Lee, Sung Yong .

IMMUNE NETWORK, 2020, 20 (01)

[9]

A systematic review on the emerging association between the occurrence of immune-related adverse events and clinical outcomes with checkpoint inhibitors in advanced cancer patients [J].

Cortellini, Alessio ;

Buti, Sebastiano ;

Agostinelli, Veronica ;

Bersanelli, Melissa .

SEMINARS IN ONCOLOGY, 2019, 46 (4-5) :362-371

[10]

A severe case of refractory esophageal stenosis induced by nivolumab and responding to tocilizumab therapy [J].

Horisberger, Alice ;

La Rosa, Stefano ;

Zurcher, Jean-Philippe ;

Zimmermann, Stefan ;

Spertini, Francois ;

Coukos, George ;

Obeid, Michel .

JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2018, 6

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