Evidence to support the existence of subgroups within the UK epidemic Clostridium difficile strain (PCR ribotype 1)

被引：21

作者：

Fawley, WN

Freeman, J

Wilcox, MH ^{[1
]}

机构：

[1] Univ Leeds, Dept Microbiol, Leeds LS2 9JT, W Yorkshire, England

[2] Leeds Gen Infirm, Old Med Sch, Leeds LS2 9JT, W Yorkshire, England

来源：

JOURNAL OF HOSPITAL INFECTION | 2003年 / 54卷 / 01期

关键词：

UK epidemic Clostridium difficile strain (PCR; ribotype); subgroup; clindamycin susceptibility;

D O I：

10.1016/S0195-6701(03)00079-3

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We used three different DNA fingerprinting techniques and clindamycin susceptibility testing to confirm that Clostridium difficile PCR ribotype I isolates can be divided into two subclones. This observation may permit a better understanding of the epidemiology and pathogenicity of C. difficile infection. (C) 2002 The Hospital Infection Society. Published by Elsevier Science Ltd. All rights reserved.

引用

页码：74 / 77

页数：4

共 17 条

[1] Typing of environmental Clostridium difficile strains.
AlSaif, NM
Brazier, JS
ONeill, G
Magee, JT
Duerden, BI
[J]. CLINICAL INFECTIOUS DISEASES, 1997, 25 : S202 - S203
[2] Typing of Clostridium difficile
Brazier, JS
[J]. CLINICAL MICROBIOLOGY AND INFECTION, 2001, 7 (08) : 428 - 431
[3] MANAGEMENT AND CONTROL OF A LARGE OUTBREAK OF DIARRHEA DUE TO CLOSTRIDIUM-DIFFICILE
CARTMILL, TDI
PANIGRAHI, H
WORSLEY, MA
MCCANN, DC
NICE, CN
KEITH, E
[J]. JOURNAL OF HOSPITAL INFECTION, 1994, 27 (01) : 1 - 15
[4] PCR AMPLIFICATION OF RIBOSOMAL-RNA INTERGENIC SPACER REGIONS AS A METHOD FOR EPIDEMIOLOGIC TYPING OF CLOSTRIDIUM-DIFFICILE
CARTWRIGHT, CP
STOCK, F
BEEKMANN, SE
WILLIAMS, EC
GILL, VJ
[J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1995, 33 (01) : 184 - 187
[5] Pulsed-field gel electrophoresis of degradation-sensitive DNAs from Clostridium difficile PCR ribotype 1 strains
Corkill, JE
Graham, R
Hart, CA
Stubbs, S
[J]. JOURNAL OF CLINICAL MICROBIOLOGY, 2000, 38 (07) : 2791 - 2792
[6] Molecular epidemiology of endemic Clostridium difficile infection
Fawley, WN
Wilcox, MH
[J]. EPIDEMIOLOGY AND INFECTION, 2001, 126 (03) : 343 - 350
[7] FREEMAN J, 2000, 40 INT C ANT AG CHEM
[8] RAPID IDENTIFICATION OF BACTERIA ON THE BASIS OF POLYMERASE CHAIN REACTION-AMPLIFIED RIBOSOMAL DNA SPACER POLYMORPHISMS
JENSEN, MA
WEBSTER, JA
STRAUS, N
[J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1993, 59 (04) : 945 - 952
[9] Epidemics of diarrhea caused by a clindamycin-resistant strain of Clostridium difficile in four hospitals.
Johnson, S
Samore, MH
Farrow, KA
Killgore, GE
Tenover, FC
Lyras, D
Rood, JI
DeGirolami, P
Baltch, AL
Rafferty, ME
Pear, SM
Gerding, DN
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (22) : 1645 - 1651
[10] Analysis of Clostridium difficile isolates from nosocomial outbreaks at three hospitals in diverse areas of Japan
Kato, H
Kato, N
Watanabe, K
Yamamoto, T
Suzuki, K
Ishigo, S
Kunihiro, S
Nakamura, I
Killgore, GE
Nakamura, S
[J]. JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (04) : 1391 - 1395

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