Lyme borreliosis: Clinical case definitions for diagnosis and management in Europe

被引:452
作者
Stanek, G. [1 ]
Fingerle, V. [2 ]
Hunfeld, K. -P. [3 ]
Jaulhac, B. [4 ]
Kaiser, R. [5 ]
Krause, A. [6 ]
Kristoferitsch, W. [7 ]
O'Connell, S. [8 ]
Ornstein, K. [9 ]
Strle, F. [10 ]
Gray, J. [11 ]
机构
[1] Med Univ Vienna, Dept Hyg & Appl Immunol, A-1095 Vienna, Austria
[2] Bavarian Food & Hlth Safety Author, Natl Reference Ctr Borrelia, Munich, Germany
[3] Goethe Univ Frankfurt, Acad Teaching Hosp, NW Med Ctr, Inst Lab Med, Frankfurt, Germany
[4] Strasbourg Univ Hosp, Dept Lab Bacteriol, Natl Reference Ctr Borrelia, Strasbourg, France
[5] Klinikum Pforzheim, Neurol Clin, Pforzheim, Germany
[6] Immanuel Krankenhaus, Rheumatol Clin, Berlin, Germany
[7] Donauspital, Sozialmed Zentrum Ost, Dept Neurol, Vienna, Austria
[8] Southampton Gen Hosp, HPA Microbiol Lab, Hlth Protect Agcy, Lyme Borreliosis Unit, Southampton SO9 4XY, Hants, England
[9] Lund Univ, Dept Clin Sci, Sect Clin & Expt Infect Med, Lund, Sweden
[10] Univ Med Ctr Ljubljana, Dept Infect Dis, Ljubljana, Slovenia
[11] Univ Coll Dublin, UCD Sch Biol & Environm Sci, Dublin 2, Ireland
关键词
Borrelia; case definitions; diagnosis; Europe; Lyme borreliosis; ACRODERMATITIS CHRONICA ATROPHICANS; BURGDORFERI SENSU-STRICTO; ERYTHEMA MIGRANS; IMMUNOGLOBULIN-G; ANTIBODY-RESPONSES; ANTIBIOTIC-THERAPY; PCR METHODS; FOLLOW-UP; DISEASE; NEUROBORRELIOSIS;
D O I
10.1111/j.1469-0691.2010.03175.x
中图分类号
R51 [传染病];
学科分类号
100201 [内科学];
摘要
P>Lyme borreliosis, caused by spirochaetes of the Borrelia burgdorferi genospecies complex, is the most commonly reported tick-borne infection in Europe and North America. The non-specific nature of many of its clinical manifestations presents a diagnostic challenge and concise case definitions are essential for its satisfactory management. Lyme borreliosis is very similar in Europe and North America but the greater variety of genospecies in Europe leads to some important differences in clinical presentation. These new case definitions for European Lyme borreliosis emphasise recognition of clinical manifestations supported by relevant laboratory criteria and may be used in a clinical setting and also for epidemiological investigations.
引用
收藏
页码:69 / 79
页数:11
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