Helicobacter pylori cagA status and s and m alleles of vacA in isolates from individuals with a variety of H-pylori associated gastric diseases

被引：61

作者：

Evans, DG

Queiroz, DMM

Mendes, EN

Evans, DJ

机构：

[1] Vet Affairs Med Ctr, Gastroenterol Sect, Bacterial Enteropathogens Lab, Houston, TX 77030 USA

[2] Baylor Coll Med, Dept Med, Houston, TX 77030 USA

[3] Univ Fed Minas Gerais, Fac Med, Lab Res Bacteriol, Belo Horizonte, MG, Brazil

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1998年 / 36卷 / 11期

关键词：

D O I：

10.1128/JCM.36.11.3435-3437.1998

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The cagA gene was detected in 100% of 16 Helicobacter pylori isolates from patients with gastric carcinoma versus 78% of 18 isolates from patients with duodenal ulcers (P = 0.343) and only 64% of 22 isolates from patients with gastritis only (P = 0.005) in Brazil. Also, there was a significant association between isolation of cagA(+) s1-type vacA H, pylori in cases of stomach cancer and ulcers as opposed to cases of gastritis only (P = 0.004), but this was not true in Houston (P = 0.238), where 94% of all isolates were cagA(+).

引用

页码：3435 / 3437

页数：3

共 22 条

[1] MOSAICISM IN VACUOLATING CYTOTOXIN ALLELES OF HELICOBACTER-PYLORI - ASSOCIATION OF SPECIFIC VACA TYPES WITH CYTOTOXIN PRODUCTION AND PEPTIC-ULCERATION [J].