Childhood tuberculosis: out of sight, out of mind?

被引:22
作者
Brent, Andrew J. [1 ]
Anderson, Suzanne T. [2 ]
Kampmann, Beate [1 ,2 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Wright Fleming Inst, Wellcome Trust Ctr Res Clin Trop Med, London W2 1PG, England
[2] Univ London Imperial Coll Sci Technol & Med, Wright Fleming Inst, Acad Dept Paediat, London W2 1PG, England
基金
英国惠康基金;
关键词
tuberculosis; children; diagnosis; epidemiology; DOTS; HIV;
D O I
10.1016/j.trstmh.2007.09.011
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Despite significant improvements in tuberculosis (TB) management under the WHO directly observed treatment, short course (DOTS) strategy, childhood TB has been relatively neglected. Children are at high risk of severe disease, and reactivation of latent infection in adulthood perpetuates the epidemic. Almost a million cases of childhood TB are estimated to occur annually, but good-quality epidemiological data are scarce due to inherent difficulties diagnosing paediatric TB. There remains an urgent need both for better diagnostic tests and for robust regional data on the true burden of disease, otherwise childhood TB wit[ remain an essentially 'invisible' and therefore neglected disease. (c) 2007 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:217 / 218
页数:2
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