Fetal growth and the risk of childhood non-CNS solid tumours in Western Australia

被引：16

作者：

Laurvick, C. L. ^{[1
]}

Milne, E. ^{[1
]}

Blair, E. ^{[1
]}

de Klerk, N. ^{[1
]}

Charles, A. K. ^{[2
,3
,4
,5
]}

Bower, C. ^{[1
]}

机构：

[1] Univ Western Australia, Telethon Inst Child Hlth Res, Ctr Child Hlth Res, Perth, WA 6872, Australia

[2] Univ Western Australia, Sch Paediat & Child Hlth, Subiaco, WA, Australia

[3] PMH Hosp, PathWest, Subiaco, WA, Australia

[4] KEMH Hosp, PathWest, Subiaco, WA, Australia

[5] Univ Western Australia, Sch Women & Infants Hlth, Subiaco, WA, Australia

来源：

BRITISH JOURNAL OF CANCER | 2008年 / 99卷 / 01期

基金：

英国医学研究理事会;

关键词：

childhood cancer; intra-uterine growth; risk factor; Cox regression;

D O I：

10.1038/sj.bjc.6604424

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Using population-based linked health data, we investigated whether the risk of certain childhood non-CNS solid tumours (n = 186) was associated with intra-uterine growth. The risk of retinoblastoma and rhabdomyosarcoma, but not other tumour types, was positively associated with increased growth, suggesting a possible role of fetal growth factors. Larger studies are needed.

引用

页码：179 / 181

页数：3

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