Three-dimensional conformal radiation therapy in bronchogenic carcinoma

Radiotherapy represents one of the primary modalities in the treatment of patients with carcinoma of the lung. Despite significant medical advancements, the outcome of therapy (local control and survival) in patients with unresectable disease is still very disappointing. Although there are some indications in the literature to suggest that higher doses of radiation may result in improved local control, the proximity of critical normal structures to the primary tumor precludes delivery of curative doses without increased risk of unacceptable complications. Three-dimensional conformal radiation therapy has shown a significant potential for improving radiation treatment planning in several sites, both for tumor coverage and sparing normal tissue. Using this technology, significant improvement in uncomplicated locoregional control of lung cancer may be possible. The following is a review of literature and analysis of the currently available information on this subject.