Group A streptococcal vaccines

被引：20

作者：

Dale, JB

机构：

[1] VA Med Ctr 11A, Memphis, TN 38104 USA

[2] Univ Tennessee, Div Infect Dis, Memphis, TN USA

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 1999年 / 13卷 / 01期

关键词：

D O I：

10.1016/S0891-5520(05)70052-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The pathogenesis of group A streptococcal infections, and antigens that contribute to protective immune responses are reviewed. Several approaches to vaccine development are discussed. Data are provided from preclinical studies of multivalent M protein-based vaccines that evoke protective antibodies in laboratory animals. Also discussed are future strategies for the development of broadly protective vaccines, and their potential impact on the incidence of streptococcal infections, and acute rheumatic fever.

引用

页码：227 / +

页数：18

共 29 条

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