Polymer-bound bis(oxazoline) as a chiral catalyst

被引：70

作者：

Hallman, K ^{[1
]}

Moberg, C ^{[1
]}

机构：

[1] Royal Inst Technol, Dept Chem Organ Chem, SE-10044 Stockholm, Sweden

来源：

TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 10期

关键词：

D O I：

10.1016/S0957-4166(01)00245-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A chiral bis(oxazoline) was grafted on ArgoGel and used in the palladium-catalysed substitution of (+/-)-1,3-diphenyl-2-propenyl acetate with dimethyl malonate. The enantioselectivity was the same as that observed when the analogous monomeric catalyst was used (94-95% e.e.), despite the fact that the C-2 symmetry of the ligand was affected when coupled to the polymer. The polymer-supported catalyst could be recycled several times after removal of precipitated Pd(0). The polymer-bound bis(oxazoline) was also applied in a zinc-catalysed Diels-Alder reaction but lower selectivity and reactivity than the monomer was observed. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：1475 / 1478

页数：4

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