Highly α-selective synthesis of disaccharide using glycosyl bromide by the promotion of phosphine oxide

被引：35

作者：

Mukaiyama, T

Kobashi, Y

机构：

[1] Kitasato Inst, Ctr Basic Res, TCI, Kita Ku, Tokyo 1140003, Japan

[2] Kitasato Univ, Kitasato Inst Life Sci, Minato Ku, Tokyo 1088641, Japan

来源：

CHEMISTRY LETTERS | 2004年 / 33卷 / 01期

关键词：

D O I：

10.1246/cl.2004.10

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple and practical method for the glycosylation of several acceptors with 2,3,4,6-tetra-0-benzyl-D-glucopyranosyl bromide was established by the promotion of phosphine oxide. The corresponding disaccharides were obtained in high yields with extremely high alpha-selectivities under almost neutral condition.

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页码：10 / 11

页数：2

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