New advances in the genetics of early onset obesity

被引:51
作者
Farooqi, IS
O'Rahilly, S
机构
[1] Wellcome Clinician Scientist Fellow,University Departments of Medicine and Clinical Biochemistry
[2] Addenbrooke's Hospital,undefined
基金
英国惠康基金;
关键词
D O I
10.1038/sj.ijo.0803056
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1149 / 1152
页数:4
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共 20 条
  • [1] Genetics of body-weight regulation
    Barsh, GS
    Farooqi, IS
    O'Rahilly, S
    [J]. NATURE, 2000, 404 (6778) : 644 - 651
  • [2] Lifting the lid on Pandora's box: the Bardet-Biedl syndrome
    Beales, PL
    [J]. CURRENT OPINION IN GENETICS & DEVELOPMENT, 2005, 15 (03) : 315 - 323
  • [3] A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
    Clément, K
    Vaisse, C
    Lahlou, N
    Cabrol, S
    Pelloux, V
    Cassuto, D
    Gourmelen, M
    Dina, C
    Chambaz, J
    Lacorte, JM
    Basdevant, A
    Bougneres, P
    Lebouc, Y
    Froguel, P
    Guy-Grand, B
    [J]. NATURE, 1998, 392 (6674) : 398 - 401
  • [4] Genetics and pathophysiology of human obesity
    Cummings, DE
    Schwartz, MW
    [J]. ANNUAL REVIEW OF MEDICINE, 2003, 54 : 453 - 471
  • [5] Overweight children and adolescents.
    Dietz, WH
    Robinson, TN
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (20) : 2100 - 2109
  • [6] Monogenic obesity in humans
    Farooqi, IS
    O'Rahilly, S
    [J]. ANNUAL REVIEW OF MEDICINE, 2005, 56 : 443 - +
  • [7] Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene
    Farooqi, IS
    Keogh, JM
    Yeo, GSH
    Lank, EJ
    Cheetham, T
    O'Rahilly, S
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (12) : 1085 - 1095
  • [8] Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
    Farooqi, IS
    Matarese, G
    Lord, GM
    Keogh, JM
    Lawrence, E
    Agwu, C
    Sanna, V
    Jebb, SA
    Perna, F
    Fontana, S
    Lechler, RI
    DePaoli, AM
    O'Rahilly, S
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2002, 110 (08) : 1093 - 1103
  • [9] Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency
    Jackson, RS
    Creemers, JWM
    Farooqi, IS
    Raffin-Sanson, ML
    Varro, A
    Dockray, GJ
    Holst, JJ
    Brubaker, PL
    Corvol, P
    Polonsky, KS
    Ostrega, D
    Becker, KL
    Bertagna, X
    Hutton, JC
    White, A
    Dattani, MT
    Hussain, K
    Middleton, SJ
    Nicole, TM
    Milla, PJ
    Lindley, KJ
    O'Rahilly, S
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2003, 112 (10) : 1550 - 1560
  • [10] Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans
    Krude, H
    Biebermann, H
    Luck, W
    Horn, R
    Brabant, G
    Grüters, A
    [J]. NATURE GENETICS, 1998, 19 (02) : 155 - 157