Progressive dysarthria - Case reports and a review of the literature

被引:15
作者
Santens, P
Van Borsel, J
Foncke, E
Meire, V
Merkx, H
De Bleecker, J
De Reuck, J
机构
[1] State Univ Ghent Hosp, Dept Neurol, B-9000 Ghent, Belgium
[2] State Univ Ghent Hosp, Speech & Hearing Rehabil Ctr, B-9000 Ghent, Belgium
[3] State Univ Ghent Hosp, PET Ctr UZ, RUG, B-9000 Ghent, Belgium
[4] AZ Menen, Dept Neurol, Menen, Belgium
关键词
dysarthria; frontotemporal degeneration; neuroimaging;
D O I
10.1159/000017125
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Two patients presenting with progressive dysarthria as the single initial manifestation of a neurodegenerative condition are described. The nature of the dysarthria as well as the additional symptoms that developed in the course of the disorder are very different in these two cases. Nevertheless, neuroimaging findings are strikingly similar and suggest bilateral involvement of posterior inferior frontal lobe structures, mainly in the dominant cerebral hemisphere. The clinical syndrome of these patients can therefore be considered an example of frontotemporal degeneration presenting without dementia or comportmental alteration, at least in the early stages. This broadens the clinical spectrum of frontotemporal degeneration and demonstrates the need for a syndromal subclassification of this nosological entity.
引用
收藏
页码:231 / 236
页数:6
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