Epithelial-to-Mesenchymal and Endothelial-to-Mesenchymal Transition From Cardiovascular Development to Disease

被引：458

作者：

Kovacic, Jason C. ^{[1
]}

Mercader, Nadia ^{[2
]}

Torres, Miguel ^{[2
]}

Boehm, Manfred ^{[3
]}

Fuster, Valentin ^{[1
,2
,4
]}

机构：

[1] Mt Sinai Sch Med, Zena & Michael A Wiener Cardiovasc Inst, New York, NY 10029 USA

[2] CNIC, Madrid, Spain

[3] NHLBI, Ctr Mol Med, Bethesda, MD 20892 USA

[4] Mt Sinai Sch Med, Marie Josee & Henry R Kravis Cardiovasc Hlth Ctr, New York, NY USA

来源：

CIRCULATION | 2012年 / 125卷 / 14期

基金：

美国国家卫生研究院;

关键词：

endothelium; epithelium; development; endocardium; vasculature; cardiovascular diseases; PLASMINOGEN-ACTIVATOR INHIBITOR-1; TRANSCRIPTION FACTOR SNAIL; EPICARDIUM-DERIVED CELLS; VASCULAR SMOOTH-MUSCLE; THYMOSIN BETA 4; CARDIAC FIBROSIS; IN-VIVO; MYOCARDIAL FIBROSIS; CELLULAR SENESCENCE; EARLY MORPHOGENESIS;

D O I：

10.1161/CIRCULATIONAHA.111.040352

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

[No abstract available]

引用

页码：1795 / 1808

页数：14

共 160 条

[1]

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease [J].

Acloque, Herve ;

Adams, Meghan S. ;

Fishwick, Katherine ;

Bronner-Fraser, Marianne ;

Angela Nieto, M. .

JOURNAL OF CLINICAL INVESTIGATION, 2009, 119 (06) :1438-1449

[2]

Noonan syndrome cardiac defects are caused by PTPN11 acting in endocardium to enhance endocardial-mesenchymal transformation [J].

Araki, Toshiyuki ;

Chan, Gordon ;

Newbigging, Susan ;

Morikawa, Lily ;

Bronson, Roderick T. ;

Neel, Benjamin G. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (12) :4736-4741

[3]

Perspectives on endothelial-to-mesenchymal transition: potential contribution to vascular remodeling in chronic pulmonary hypertension [J].

Arciniegas, Enrique ;

Frid, Maria G. ;

Douglas, Ivor S. ;

Stenmark, Kurt R. .

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2007, 293 (01) :L1-L8

[4]

Thymosin Beta 4 Is Dispensable for Murine Cardiac Development and Function [J].

Banerjee, Indroneal ;

Zhang, Jianlin ;

Moore-Morris, Thomas ;

Lange, Stephan ;

Shen, Tao ;

Dalton, Nancy D. ;

Gu, Yusu ;

Peterson, Kirk L. ;

Evans, Sylvia M. ;

Chen, Ju .

CIRCULATION RESEARCH, 2012, 110 (03) :456-U188

[5]

The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells [J].

Batlle, E ;

Sancho, E ;

Franci, C ;

Domínguez, D ;

Monfar, M ;

Baulida, J ;

de Herreros, AG .

NATURE CELL BIOLOGY, 2000, 2 (02) :84-89

[6]

UNDIFFERENTIATED VASCULAR ENDOTHELIAL-CELLS IN CORONARY ALLOGRAFT ATHEROSCLEROSIS [J].

BERANEK, JT ;

CAVAROCCHI, NC .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 1990, 28 (01) :127-128

[7]

Transforming growth factor-β1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism [J].

Bhowmick, NA ;

Ghiassi, M ;

Bakin, A ;

Aakre, M ;

Lundquist, CA ;

Engel, ME ;

Arteaga, CL ;

Moses, HL .

MOLECULAR BIOLOGY OF THE CELL, 2001, 12 (01) :27-36

[8]

Thymosin β4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair [J].

Bock-Marquette, I ;

Saxena, A ;

White, MD ;

DiMaio, JM ;

Srivastava, D .

NATURE, 2004, 432 (7016) :466-472

[9]

A myocardial lineage derives from Tbx18 epicardial cells [J].

Cai, Chen-Leng ;

Martin, Jody C. ;

Sun, Yunfu ;

Cui, Li ;

Wang, Lianchun ;

Ouyang, Kunfu ;

Yang, Lei ;

Bu, Lei ;

Liang, Xingqun ;

Zhang, Xiaoxue ;

Stallcup, William B. ;

Denton, Christopher P. ;

McCulloch, Andrew ;

Chen, Ju ;

Evans, Sylvia M. .

NATURE, 2008, 454 (7200) :104-U4

[10]

Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart [J].

Cai, CL ;

Liang, XQ ;

Shi, YQ ;

Chu, PH ;

Pfaff, SL ;

Chen, J ;

Evans, S .

DEVELOPMENTAL CELL, 2003, 5 (06) :877-889

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