Effects of Boswellic acid of Boswellia serrata and other triterpenic acids on the complement system

被引：31

作者：

Knaus, U ^{[1
]}

Wagner, H ^{[1
]}

机构：

[1] UNIV MUNICH, INST PHARMACEUT BIOL, D-80333 MUNICH, GERMANY

来源：

PHYTOMEDICINE | 1996年 / 3卷 / 01期

关键词：

beta-boswellic acid; Boswellia serrata; classical and alternative complement pathway;

D O I：

10.1016/S0944-7113(96)80016-X

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

beta-boswellic acid (BA), one major constituent of the resin of Boswellia serrata and other triterpenic acids of plant origin (crataegolic-, ursolic-, oleanolic- and glycyrrhetic acid) were found to possess anti-complementary activity in the classical and in the alternative complement pathway. Significant reduction of immunohemolysis in vitro was observed at BA concentrations between 0.005-0.1 mM with an IC50 value of about 10 mu mol/1.

引用

页码：77 / 80

页数：4

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