Long-term benzimidazole treatment of alveolar echinococcosis with hematogenic subcutaneous and bone dissemination

被引：15

作者：

Scheuring, UJ

Seitz, HM

Wellmann, A

Hartlapp, JH

Tappe, D

Brehm, K

Spengler, U

Sauerbruch, T

Rockstroh, JK

机构：

[1] Univ Frankfurt Hosp, Dept Hematol Oncol Infect Dus & Rheumatol, D-60596 Frankfurt, Germany

[2] Univ Bonn, Inst Med Parasitol, D-53105 Bonn, Germany

[3] Univ Bonn, Inst Pathol, D-53105 Bonn, Germany

[4] Stadt Kliniken Osnabruck, Dept Hematol & Oncol, D-49076 Osnabruck, Germany

[5] Univ Wurzburg, Inst Hyg & Microbiol, D-97080 Wurzburg, Germany

[6] Univ Hosp Bonn, Dept Internal Med, D-53105 Bonn, Germany

来源：

MEDICAL MICROBIOLOGY AND IMMUNOLOGY | 2003年 / 192卷 / 04期

关键词：

alveolar echinococcosis; Echinococcus multilocularis larva infection subcutaneous involvement; bone involvement; albendazole/mebendazole;

D O I：

10.1007/s00430-002-0171-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report a case of advanced alveolar echinococcosis (AE) that presented like a malignant tumor. It was diagnosed histologically from a subcutaneous nodule with skin inflammation on the right leg. Additionally, the patient showed bone metastases in the lower thoracic spine and the left third toe. This is the first case with proven hematogenic spread of AE to a subcutaneous site. The patient was treated with albendazole and remained stable for 6 years. When progression of AE occurred the therapy was changed to mebendazole, resulting in a stable condition for further 4 years.

引用

页码：193 / 195

页数：3

共 10 条

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