Is TGF-β1 the key to suppression of human asthma?

被引：55

作者：

Nakao, A ^{[1
]}

机构：

[1] Juntendo Univ, Sch Med, Allergy Res Ctr, Bunkyo Ku, Tokyo 1138421, Japan

来源：

TRENDS IN IMMUNOLOGY | 2001年 / 22卷 / 03期

关键词：

D O I：

10.1016/S1471-4906(00)01827-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Transforming growth factor beta1 (TGF-beta1) is produced by many types of cells that are activated in the asthmatic response. Recent studies have highlighted this cytokine as an important negative regulator in an experimental model of asthma, Although the role of TGF-beta1 in human asthma remains obscure, data derived from animal models have encouraged the further investigation of such suppression mechanisms in order to develop novel therapies for asthma.

引用

页码：115 / 118

页数：4

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